GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | trans | rs965513 | 1 | rs7021576 | chr9:100540541 | EPDR1 | chr7:37960163-37991539:+ | 0.32 | 7.06 | 5.96E-12 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7021576 | chr9:100540541 | GGT5 | chr22:24615623-24641110:- | 0.26 | 6.04 | 3.1E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7021576 | chr9:100540541 | LRRC42 | chr1:54412037-54433839:+ | -0.24 | -6.3 | 6.58E-10 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7021576 | chr9:100540541 | NKX6-1 | chr4:85414436-85419387:- | 0.5 | 8.65 | 7.61E-17 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7021576 | chr9:100540541 | PLCE1 | chr10:95753746-96088146:+ | 0.28 | 6.39 | 3.94E-10 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7027030 | chr9:100550455 | BMPR1A | chr10:88516396-88684944:+ | -0.24 | -6.27 | 8.15E-10 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7027030 | chr9:100550455 | CLDN2 | chrX:106143394-106174091:+ | 0.26 | 6.07 | 2.61E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7027030 | chr9:100550455 | EML5 | chr14:89081205-89259157:- | 0.3 | 6.96 | 1.12E-11 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7027030 | chr9:100550455 | EPDR1 | chr7:37960163-37991539:+ | 0.33 | 7.31 | 1.1E-12 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7027030 | chr9:100550455 | GGT5 | chr22:24615623-24641110:- | 0.26 | 6.06 | 2.78E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7027030 | chr9:100550455 | LRRC42 | chr1:54412037-54433839:+ | -0.23 | -5.95 | 5.14E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7027030 | chr9:100550455 | MALL | chr2:110841452-110874143:- | 0.29 | 5.91 | 6.44E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7027030 | chr9:100550455 | NKX6-1 | chr4:85414436-85419387:- | 0.49 | 8.55 | 1.71E-16 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7027030 | chr9:100550455 | PLCE1 | chr10:95753746-96088146:+ | 0.27 | 6.15 | 1.6E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7027030 | chr9:100550455 | TTC8 | chr14:89290497-89344334:+ | 0.24 | 5.97 | 4.67E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |